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| Single Dose Oral and Intravenous Pharmacokinetics and Tissue Distribution of a Novel Hesperetin Derivative MTBH in Rats. | |||
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| 분류 | pharmacokinetics | 조회 | 2275 |
| 발행년도 | 2015 | 등록일 | 2015-10-17 |
| 출처 | Eur J Drug Metab Pharmacokinet (바로가기) | ||
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BACKGROUND:
MTBH, a novel hesperetin derivative, possesses in vivo hepatoprotective effects against carbon tetrachloride (CCl4)-induced acute liver injury in Institute of Cancer Research (ICR) mice.
OBJECTIVES:
This study investigated the pharmacokinetics and tissue distribution of MTBH and its conjugated metabolites in rats after a single dose of MTBH.
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