OBJECTIVE:

 

In this study, we assessed the feasibility and clinical advantages of single photon emission computed tomography with CT (SPECT/CT) for sentinel lymph node (SLN) detection in vulvar cancer.

 

METHODS:

 

This is a unicentric prospective trial. Vulvar cancer patients underwent preoperative SLN marking (10MBq Technetium(TC)-99m-nanocolloid) and subsequent planar lymphoscintigraphy (LSG) and SPECT/CT for SLN visualization. Directly before surgery, patent blue dye was injected. We assessed detection rates of SPECT/CT and those of planar LSG and intraoperative detection. We analysed the sensitivity, negative predictive value and false negative rate.

 

(후략)