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| Effects of Hemodialysis on Methadone Pharmacokinetics and QTc. | |||
|---|---|---|---|
| 분류 | pharmacokinetics | 조회 | 1277 |
| 발행년도 | 2015 | 등록일 | 2015-09-24 |
| 출처 | Clin Ther (바로가기) | ||
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PURPOSE:
Effects of hemodialysis on pharmacokinetic properties and QTc were studied in 4 patients taking daily methadone dose of 100 mg (range, 60-120 mg).
METHODS:
Methadone in serum, dialysate, and urine were measured by LC-MS/MS. QTc was calculated with Bazett's formula.
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