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| Design, Synthesis, and Characterization of SO2-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery. | |||
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| 분류 | drug discovery | 조회 | 1383 |
| 발행년도 | 2015 | 등록일 | 2015-07-14 |
| 출처 | Org Lett (바로가기) | ||
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A set of novel SO2-containing azabicyclo[3.n.1]alkanes has been synthesized by the double-Mannich annulation of of the corresponding monocyclic S-ketones. These compounds have been rationally designed as 3D-shaped, conformationally restricted SO2-containing building blocks for drug discovery.
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